abstract：BACKGROUND:Several technical modifications in portal vein (PV) reconstruction have shown excellent outcomes in pediatric liver transplantation (LT); however, which procedure is the best for PV reconstruction of the hypoplastic PV in pediatric LT remains unclear. METHODS:One hundred sixteen pediatric patients aged 1 or...

journal_title：Transplantation

authors： Sakamoto S,Uchida H,Kitajima T,Shimizu S,Yoshimura S,Takeda M,Hirata Y,Fukuda A,Kasahara M

更新日期：2020-01-01 00:00:00

abstract：BACKGROUND:Hepatocellular carcinoma (HCC) is the most common primary malignant liver tumor. Currently, liver transplantation may be the optimal treatment for HCC in cirrhotic patients. Patient selection is currently based on tumor size. We developed a program to offer liver transplantation to selected patients with HCC...

journal_title：Transplantation

authors： Victor DW 3rd,Monsour HP Jr,Boktour M,Lunsford K,Balogh J,Graviss EA,Nguyen DT,McFadden R,Divatia MK,Heyne K,Ankoma-Sey V,Egwim C,Galati J,Duchini A,Saharia A,Mobley C,Gaber AO,Ghobrial RM

更新日期：2020-01-01 00:00:00

abstract：BACKGROUND:DBA/2J kidney allografts, but not heart allografts, are spontaneously accepted indefinitely in C57BL/6 (B6) mice, through regulatory tolerance mechanism dependent on Foxp3 cells. In contrast, B6 kidneys are rejected within a week in DBA/2J recipients. We hypothesized that the tolerogenic difference of the ki...

journal_title：Transplantation

authors： Oh NA,O'Shea T,Ndishabandi DK,Yuan Q,Hong S,Gans J,Ge J,Gibney S,Chase C,Yang C,Rosales I,Shinoda K,Drew B,Kojima L,Russell PS,Madsen JC,Colvin RB,Alessandrini A

更新日期：2020-01-01 00:00:00

abstract：BACKGROUND:Kidneys from infectious risk donors (IRD) confer substantial survival benefit in adults, yet the benefit of IRD kidneys to pediatric candidates remains unclear in the context of high waitlist prioritization. METHODS:Using 2010-2016 Scientific Registry of Transplant Recipients data, we studied 2417 pediatric...

journal_title：Transplantation

authors： Bowring MG,Jackson KR,Wasik H,Neu A,Garonzik-Wang J,Durand C,Desai N,Massie AB,Segev DL

更新日期：2019-12-01 00:00:00

abstract：BACKGROUND:Increased use of pediatric deceased donor kidneys could enlarge the deceased donor kidney pool. Kidney transplant outcomes from small pediatric donors were compared with those from ideal kidney (IK) and expanded criteria kidney (ECK) donors to understand the optimal use of pediatric donor kidneys. METHODS:K...

journal_title：Transplantation

authors： Suneja M,Kuppachi S,Katz D,Hunsicker L

更新日期：2019-12-01 00:00:00

abstract：BACKGROUND:Vaccine-preventable viral infections are associated with increased risk of morbidity and mortality in immunocompromised patients. Current guidelines recommend routine screening and vaccination of all patients before solid organ transplantation. We studied rates of immunity against vaccine-preventable viruses...

journal_title：Transplantation

authors： Gardiner A,Liu K,Bonnichsen M,Joshi V,Davis RJ,Strasser SI

更新日期：2019-11-01 00:00:00

abstract：BACKGROUND:Patients at greatest risk of posttransplant lymphoproliferative disorder (PTLD) are those who acquire primary Epstein-Barr virus (EBV) infection after solid organ transplantation. The incidence of PTLD among patients who are EBV-seropositive before transplant is lower, and little is known about the differenc...

journal_title：Transplantation

authors： L'Huillier AG,Dipchand AI,Ng VL,Hebert D,Avitzur Y,Solomon M,Ngan BY,Yeung S,Stephens D,Punnett AS,Barton M,Allen UD

更新日期：2019-11-01 00:00:00

abstract：BACKGROUND:In a recent trial, targeted mild hypothermia in brain-dead organ donors significantly reduced the incidence of delayed graft function after kidney transplantation. This trial was stopped early for efficacy. Here, we report long-term graft survival for all organs along with donor critical care end points. ME...

journal_title：Transplantation

authors： Malinoski D,Patel MS,Axelrod DA,Broglio K,Lewis RJ,Groat T,Niemann CU

更新日期：2019-11-01 00:00:00

abstract：BACKGROUND:The innovative pure laparoscopic living donor right hepatectomy (LLDRH) procedure for liver transplantation has never been fully compared to open living donor right hepatectomy (OLDRH). We aimed to compare the donor safety and graft results of pure LLDRH to those of OLDRH. METHODS:From May 2013 to July 2017...

journal_title：Transplantation

authors： Park J,Kwon DCH,Choi GS,Kim SJ,Lee SK,Kim JM,Lee KW,Chung YJ,Kim KS,Lee JS,Rhu J,Kim GS,Gwak MS,Ko JS,Lee JE,Lee S,Joh JW

更新日期：2019-10-01 00:00:00

abstract：BACKGROUND:Neighborhood poverty has been associated with worse outcomes after live donor kidney transplantation (LDKT), and prior work suggests that women with kidney disease may be more susceptible to the negative influence of poverty than men. As such, our goal was to examine whether poverty differentially affects wo...

journal_title：Transplantation

authors： Purnell TS,Luo X,Crews DC,Bae S,Ruck JM,Cooper LA,Grams ME,Henderson ML,Waldram MM,Johnson M,Segev DL

更新日期：2019-10-01 00:00:00

abstract：BACKGROUND:There is a lack of information about survival after dropout from the liver transplant waiting list. Therefore, we aimed to assess the overall survival, and risk factors for death, after waiting list dropout due to hepatocellular carcinoma (HCC) progression. METHODS:We assessed patients who dropped out of th...

journal_title：Transplantation

authors： Gorgen A,Rosales R,Sadler E,Beecroft R,Knox J,Dawson LA,Ghanekar A,Grant D,Greig PD,Sapisochin G

更新日期：2019-10-01 00:00:00

abstract：BACKGROUND:Status 1A patients are prioritized over liver disease patients regardless of Model for End-stage Liver Disease (MELD) score. We aimed to identify groups with high waitlist mortality in Status 1A and MELD ≥40 patients to determine who would most benefit from transplantation. METHODS:Data on patients listed a...

journal_title：Transplantation

authors： Safwan M,Nwagu U,Collins K,Abouljoud M,Nagai S

更新日期：2019-10-01 00:00:00

abstract：BACKGROUND:Although proportionally more veterans live in rural areas compared to nonveterans, the impact of rurality status on kidney transplantation (KTP) access among veterans is unknown. Our objective was to study KTP rates among veterans listed for KTP and to compare the impact of rurality status on KTP rates among...

journal_title：Transplantation

authors： O'Shea AMJ,Franciscus CL,Kaboli PJ,Kalil RS

更新日期：2019-09-01 00:00:00

abstract：BACKGROUND:Acute kidney injury (AKI) after living donor liver transplantation (LDLT) is associated with increased mortality. We sought to identify associations between intraoperative hemodynamic variables and postoperative AKI. METHODS:We retrospectively reviewed 734 cases of LDLT. Intraoperative hemodynamic variables...

journal_title：Transplantation

authors： Kim WH,Oh HW,Yang SM,Yu JH,Lee HC,Jung CW,Suh KS,Lee KH

更新日期：2019-09-01 00:00:00

abstract：BACKGROUND:In France, the need for continuous monitoring of transplant center performance has recently become apparent. Cumulative sum (CUSUM) monitoring of transplantation is already been used to monitor transplant outcomes in the United Kingdom and in the United States. Because CUSUM monitoring can be applied by diff...

journal_title：Transplantation

authors： Alexandrine B,Savoye E,Pessione F,Cantrelle C,Jasseron C,Santin G,Bastien O,Legeai C

更新日期：2019-09-01 00:00:00

abstract：BACKGROUND:We previously reported the novel activity of alloprimed CD8 T cells that suppress posttransplant alloantibody production. The purpose of the study is to investigate the expression and role of CXCR5 on antibody-suppressor CD8 T-cell function. METHODS:C57BL/6 mice were transplanted with FVB/N hepatocytes. All...

journal_title：Transplantation

authors： Zimmerer JM,Ringwald BA,Elzein SM,Avila CL,Warren RT,Abdel-Rasoul M,Bumgardner GL

更新日期：2019-09-01 00:00:00

abstract：:Complement plays important roles in both ischemia-reperfusion injury (IRI) and antibody-mediated rejection (AMR) of solid organ allografts. One approach to possibly improve outcomes after transplantation is the use of C1 inhibitor (C1-INH), which blocks the first step in both the classical and lectin pathways of compl...

journal_title：Transplantation

authors： Berger M,Lefaucheur C,Jordan SC

更新日期：2019-09-01 00:00:00

abstract：BACKGROUND:Although chronic kidney disease (CKD) is still a common complication, the prognosis of kidney function after liver transplantation (LT) is not well known. Moreover, kidney function after LT in children with renal involvement is unknown. METHODS:We retrospectively analyzed patients aged <20 years who underwe...

journal_title：Transplantation

authors： Sato M,Kaneko T,Ogura M,Kamei K,Ito S,Fukuda A,Sakamoto S,Kasahara M,Ishikura K

更新日期：2019-08-01 00:00:00

abstract：BACKGROUND:Antibody-mediated rejection (AMR) is a leading cause of morbidity and mortality after kidney transplantation. Early diagnosis and treatment of subclinical AMR based on the donor-specific antibody (DSA) testing may result in better outcomes. METHODS:We tested this hypothesis in 220 kidney transplant recipien...

journal_title：Transplantation

authors： Parajuli S,Joachim E,Alagusundaramoorthy S,Blazel J,Aziz F,Garg N,Muth B,Mohamed M,Mandelbrot D,Zhong W,Djamali A

更新日期：2019-08-01 00:00:00

abstract：BACKGROUND:Proliferative glomerulonephritis with monoclonal immunoglobulin deposits (PGNMID) is a distinct form of glomerulonephritis that often recurs after kidney transplantation causing severe graft injury and often failure. METHODS:We describe post transplant outcomes and response to therapy in 20 recipients with ...

journal_title：Transplantation

authors： Buxeda A,Said SM,Nasr SH,Leung N,El Ters M,Cosio FG

更新日期：2019-07-01 00:00:00

abstract：BACKGROUND:Ex situ normothermic machine perfusion (NMP) can be used to assess viability of suboptimal donor livers before implantation. Our aim was to assess the diagnostic accuracy of bile biochemistry for the assessment of bile duct injury (BDI). METHODS:In a preclinical study, 23 human donor livers underwent 6 hour...

journal_title：Transplantation

authors： Matton APM,de Vries Y,Burlage LC,van Rijn R,Fujiyoshi M,de Meijer VE,de Boer MT,de Kleine RHJ,Verkade HJ,Gouw ASH,Lisman T,Porte RJ

更新日期：2019-07-01 00:00:00

abstract：BACKGROUND:To investigate the transparency, biocompatibility, and safety of human-derived acellular dermal matrix for application in corneal stromal transplantation. METHODS:Twenty-four patients (24 eyes) with pellucid marginal corneal degeneration were enrolled, and intrastromal keratoplasty was performed with human-...

journal_title：Transplantation

authors： Jiang X,Wang Y,Qiu W,Huang C,Liu Z,Ding T,Shi D,Li X

更新日期：2019-06-01 00:00:00

abstract：BACKGROUND:Despite early skepticism, the field of vascularized composite allotransplantation (VCA) has demonstrated feasibility. The ethics of VCA have moved past doubts about the morality of attempting such transplants to how to conduct them ethically. METHODS:Leaders of each program performing and/or evaluating VCA ...

journal_title：Transplantation

authors： Caplan AL,Parent B,Kahn J,Dean W,Kimberly LL,Lee WPA,Rodriguez ED

更新日期：2019-06-01 00:00:00

abstract：BACKGROUND:The relationship between institutional case volume and clinical outcomes after living donor liver transplantation is not clarified. METHODS:We conducted a nationwide retrospective cohort study using the database of Korean National Healthcare Insurance Service. Between January 2007 and December 2016, 7073 ad...

journal_title：Transplantation

authors： Yoo S,Jang EJ,Yi NJ,Kim GH,Kim DH,Lee H,Jung CW,Ryu HG

更新日期：2019-05-01 00:00:00

abstract：BACKGROUND:Survival after lung transplantation is mainly limited by the development of chronic lung allograft dysfunction (CLAD). The aim of this study was to investigate if platelet inhibition by clopidogrel has a functionally relevant influence on the microvascular integrity of orthotopic tracheal allografts as an an...

journal_title：Transplantation

authors： Heim C,Khan MA,von Silva-Tarouca B,Kuckhahn A,Stamminger T,Ramsperger-Gleixner M,Nicolls MR,Weyand M,Ensminger SM

更新日期：2019-05-01 00:00:00

abstract：BACKGROUND:Little is known about associations between low physical activity (PA) and its correlates and outcomes in solid organ transplant recipients. This systematic review with meta-analysis examined correlates and outcomes associated with low PA (ie, not meeting individual study's definition of being physically acti...

journal_title：Transplantation

authors： Berben L,Engberg SJ,Rossmeissl A,Gordon EJ,Kugler C,Schmidt-Trucksäss A,Klem ML,Sereika SM,De Simone P,Dobbels F,De Geest SM,B-SERIOUS consortium.

更新日期：2019-04-01 00:00:00

abstract：BACKGROUND:Whether kidney transplant recipients who were treated for a malignant tumor before transplantation are at an increased risk of developing a tumor posttransplantation has not been adequately quantified and characterized. METHODS:We studied more than 270 000 patients on whom pretransplant and posttransplant m...

journal_title：Transplantation

authors： Unterrainer C,Opelz G,Döhler B,Süsal C,Collaborative Transplant Study.

更新日期：2019-03-01 00:00:00

abstract：BACKGROUND:In the United States, 1 in 10 infants and 1 in 20 older children die on the liver transplant waiting list. Increasing split liver transplantation could increase organ availability for these children, without decreasing transplants in adults. METHODS:Using United Network for Organ Sharing Standard Transplant...

journal_title：Transplantation

authors： Perito ER,Roll G,Dodge JL,Rhee S,Roberts JP

更新日期：2019-03-01 00:00:00

abstract：BACKGROUND:Heart transplantation (HTx) remains the most effective long-term treatment for advanced heart failure. Primary graft dysfunction (PGD) continues to be a potentially life-threatening early complication. In 2014, a consensus statement released by International Society for Heart and Lung Transplantation (ISHLT)...

journal_title：Transplantation

authors： Avtaar Singh SS,Banner NR,Rushton S,Simon AR,Berry C,Al-Attar N

更新日期：2019-02-01 00:00:00

abstract：:Modification of pathogenic antibodies for autoimmune diseases illuminated the biologic relevance of B cells, plasma cells, and pathogenic antibodies in autoimmunity. They have also rejuvenated interest in how B cells mediate multiple effector functions that include antibody production, antigen presentation to T cells,...

journal_title：Transplantation

authors： Jordan SC,Ammerman N,Choi J,Huang E,Peng A,Sethi S,Najjar R,Toyoda M,Lim K,Louie S,Vo A

更新日期：2019-02-01 00:00:00

abstract：BACKGROUND:Recent changes in policies guiding allocation of transplant kidneys are predicted to increase sharing between distant geographic regions. The potential exists for an increase in cold ischemia time (CIT) with resulting increases in delayed graft function (DGF) and transplant-related costs (TRC). We sought to ...

journal_title：Transplantation

authors： Serrano OK,Vock DM,Chinnakotla S,Dunn TB,Kandaswamy R,Pruett TL,Feldman R,Matas AJ,Finger EB

更新日期：2019-02-01 00:00:00

abstract：:Chronic kidney disease is common in patients with multiple myeloma. Historically, individuals with end-stage renal disease and multiple myeloma did poorly with renal transplantation due to higher mortality rates from the malignancy itself or associated comorbidities. However, over the past 2 decades, there have been s...

journal_title：Transplantation

authors： Huskey JL,Heilman RL,Khamash H,Fonseca R

更新日期：2018-12-01 00:00:00

abstract：BACKGROUND:A previous donor intervention trial found that induction of mild therapeutic hypothermia in the brain-dead donor reduced the dialysis requirement after kidney transplantation. Consequences on the performance of cardiac allografts after transplantation were not explored to date. METHODS:Cohort study investig...

journal_title：Transplantation

authors： Schnuelle P,Benck U,Krämer BK,Yard BA,Zuckermann A,Wagner F,Szabo G,Borggrefe M,Karck M,Gummert J

更新日期：2018-11-01 00:00:00

abstract：BACKGROUND:Antibody-mediated rejection (AMR) remains associated with reduced kidney graft survival and no clear prognostic marker is available. METHODS:We investigated whether donor-specific antibodies (DSA) ability to bind C1q in comparison with AMR C4d status, both indirect signs of complement activation, improve ri...

journal_title：Transplantation

authors： Malheiro J,Santos S,Tafulo S,Dias L,Martins S,Fonseca I,Almeida M,Pedroso S,Beirão I,Castro-Henriques A,Cabrita A

更新日期：2018-11-01 00:00:00

abstract：:Invasive aspergillosis and mucormycosis are life-threatening infections in solid organ and hematopoietic cell transplant recipients. Despite medical advancements in the care of these patients and the availability of new mold-active drugs, the outcomes remain suboptimal. Therefore, there has been increased interest in ...

journal_title：Transplantation

authors： Haidar G,Singh N

更新日期：2018-11-01 00:00:00

abstract：BACKGROUND:Data on liver transplant (LT) outcomes using deceased donors with heavy drinking (HD) (>2 drinks per day) are scanty. METHODS:Using the United Network for Organ Sharing database (2002-2014), we examined outcomes after LT in adults comparing deceased HD donors with non-HD (ND) donors. RESULTS:Of 56 182 firs...

journal_title：Transplantation

authors： Arora SS,Chahal KS,Axley P,Eckhoff DE,Kuo YF,Satapathy SK,Wiesner R,Singal AK

更新日期：2018-11-01 00:00:00

abstract：BACKGROUND:Whether cytomegalovirus (CMV)-specific cell-mediated immunity (CMI) at prophylaxis cessation predicts D+/R+ kidney transplants at risk of late-onset CMV infection after receiving distinct induction therapies is still not well characterized. METHODS:We prospectively assessed CMV-specific CMI predicting late-...

journal_title：Transplantation

authors： Jarque M,Melilli E,Crespo E,Manonelles A,Montero N,Torras J,Cruzado JM,Luque S,Gil-Vernet S,Grinyó JM,Bestard O

更新日期：2018-11-01 00:00:00

abstract：BACKGROUND:Cold ischemia-reperfusion injury is unavoidable during organ transplantation, and prolonged preservation is associated with poorer function recovery. Cardiotrophin-1 (CT-1) is an IL-6 family cytokine with cytoprotective properties. This preclinical study in rats tested whether CT-1 mitigates cold renal ische...

journal_title：Transplantation

authors： García-Cenador B,Blanco-Gozalo V,López-Montañés D,Sanz Giménez-Rico JR,López-Novoa JM,López-Hernández FJ

更新日期：2018-10-01 00:00:00

abstract：BACKGROUND:The aim of this study was to compare the pharmacokinetic profile, tolerability, and safety of a novel once-daily extended-release formulation of tacrolimus (LCPT) with that of once-daily prolonged-release tacrolimus (ODT) in stable adult lung transplant (LT) recipients. METHODS:Phase II, open-label, single-...

journal_title：Transplantation

authors： Sintes H,Sáez-Giménez B,Berastegui C,López-Meseguer M,Monforte V,Bravo C,Vima J,Gómez-Ollés S,Roman A

更新日期：2018-10-01 00:00:00

abstract：BACKGROUND:Pregnancy after heart transplantation (HTx) may expose the recipient to hemodynamic and immunologic risks and the newborn to toxic effects of immunosuppressive therapy. Adequate preconception counseling is crucial to identify optimal timing and to modify immunosuppressive therapy to minimize risks for both t...

journal_title：Transplantation

authors： Macera F,Occhi L,Masciocco G,Varrenti M,Frigerio M

更新日期：2018-09-01 00:00:00